Klovinal Vaginal Pessary | How to use it effectively, Side effects and more

Klovinal, commonly known as a pessary, is a vaginal tablet that contains metronidazole, clotrimazole, and lactobacillus spores. It's utilised to get rid of a vaginal infection. Both Metronidazole and Clotrimazole kill both good and nasty vaginal infections.

The beneficial bacteria in the vaginal area protect it from infection and disease. Lactobacillus spores replenish the vaginal flora with new beneficial bacteria, restoring normal vaginal flora.

Each box of Klovinal vaginal pills contains six tablets. The pessaries are bullet-shaped white to off-white tablets. It is manufactured in India by bliss GVS pharma ltd and distributed in Nigeria by sea-green medicines ltd.

Composition Of Klovinal Vaginal Tablet

Each Pessary contains:

• Metronidazole BP 500 mg
• Clotrimazole BP 100mg
• Lactobacillus Spores 150 million
• Excipients qs

Klovinal is a vaginal infection treatment that combines clotrimazole, metronidazole (Flagyl), and lactobacillus spores to treat both fungal and bacterial infections such as vulvovaginal candidiasis (yeast infection), pelvic inflammatory disease (PID), bacterial vaginosis, and trichomoniasis.

Klovinal is a pessary that treats the causes of vaginitis while also restoring the vaginal acidic balance (or normal flora). It's great for preventing recurrent vaginal infections.

Mycoten, Sabreten, Canesten, and candid V6 are other typical medications used to treat vaginal infections such as candidiasis, vaginosis, and trichomoniasis.

They are not wide spectrum since they only contain clotrimazole, which means they only cure fungal infections. Clotrimazole is not effective against bacterial or protozoan illnesses.

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How to use Klovinal Vaginal Tablet

1 wash your hands clean

2. Do not enter the pessary. If the foil wrapper seems soft, run it under cold water or store it in the refrigerator for a few minutes to stiffen it before removing it.

3. Take one pessary from the strip.

4. Peel away any foil or plastic covering from the pessary.

5. Sit or lay down with your legs apart and your knees bent.

6. Using your fingers, gently insert the pessary as far as comfortably possible into the vagina.

7. Wash your hands again when done.

8. Stay in that laying posture for approximately an hour.

Tips on the effective use of Klovinal Vaginal Tablet

• Once a day, insert one (1) Klovinal pessary as deeply as possible into the vaginal canal using your fingers or an applicator. It should be used for at least six (6) days, ideally before going to bed.
• Even if your symptoms go away after a few days or your menstrual cycle begins, keep taking this medicine every day for the whole time suggested. Stopping klovinal too soon may cause the infection to recur, worsening and becoming more difficult to cure.
• Please with your doctor before taking Klovinal if you are pregnant. Klovinal is not recommended for usage during pregnancy since it might cause birth abnormalities.

Price of Klovinal

In Nigeria, the cost/price of Klovinal is roughly #4,000 naira per packet. There are 6 pills in each package. In Ghana, the price of KLOVINAL is 10 cedis.

Side effects of Klovinal

• Burns
• Scorching sensations
• Stinging sensations in the vaginal area
• Minor aches
• Lower abdominal cramps
• stains from leaking after dissolving,
• Nausea and vomiting

All these have been reported by women who use Klovinal pessary. It's possible that some adverse effects haven't been reported yet.

Many women who have used Klovinal previously have nearly always experienced pain in the lower abdomen after taking it, this may be real based on anecdotal adverse effects observed.

Many women who have used it before have almost always reported pain in the lower abdomen after taking it.

Note: While using Klovinal Vaginal Tablet, avoid using tampons, douches, vaginal wash, feminine wash, yoni pearls, baking soda, apple cedar vinegar, spermicides, or other vaginal products.

Klovinal Pharmacodynamics

Clotrimazole is a topical or intravaginal antifungal medication with a wide range of activity. It kills yeast and dermatophytes, as well as certain Gram-positive bacteria, including Staphylococcus aureus and Trichomonas.

Clotrimazole works by interfering with cell wall lipids to change the permeability of fungal cell walls.

Trichomonas vaginalis is one of the protozoa that may be treated with metronidazole. It's antibacterial.

Metronidazole is used to treat and prevent anaerobic infections in those who are sensitive to protozoal infections.

Metronidazole is used to treat bacterial infections such as bacterial vaginosis (nonspecific vaginitis).

The vaginal ecology is active, with roughly 109 bacterial colony forming units per gramme of vaginal fluid under typical conditions.

Lactobacilli dominate the natural bacterial flora. Lactobacilli metabolise lactic acids and other organic acids from glycogen, keeping the vaginal pH between 3.8 and 4.2.

Bacteria and other pathogenic organisms are prevented from overgrowing in an acidic environment.

The Lactobacilli flora decreases as a result of vaginal infections such as bacterial vaginosis, trichomoniasis, and vulvovaginal candidiasis, and the vaginal pH rises to more than 4.5.

A musty or fishy odour develops as a result of anaerobic bacteria. Lactobacillus is found as spores. It's used to recolonize the vaginal flora and keep the pH between 3.8 and 4.2 in the vaginal area.

Klovinal Pharmacokinetics

Clotrimazole penetrates the epidermis when applied topically, but little or no systemic absorption has been reported after vaginal administration. Metronidazole is reported to be poorly absorbed from vaginal pessaries.

The vaginal flora is recolonized by Lactobacillus sporogenes.

Contraindications

Patients who are known to be hypersensitive to topical Imidazoles should avoid Klovinal pessary.

Precautions And Warnings

If irritation or sensitivity develops while using Klovinal pessary, the medication should be stopped and appropriate therapy started. If Klovinal pessary treatment fails to work, microbiological tests should be performed to confirm the diagnosis and rule out other pathogens before starting another round of anti-mucolytic therapy.

Lactation and pregnancy

Only if the benefits outweigh the risk to the foetus should Klovinal pessary be given to a pregnant or lactating mother.

Interaction

Antibiotics with lactobacillus activity should be avoided. Home remedies such as cedar vinegar, baking soda, and others fall into this category.

Klovinal Indications And Use

For vaginal infections such as trichomoniasis, bacterial vaginosis, and vulvovaginal candidiasis, Klovinal Pessary is prescribed.

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Frequently Asked Questions about Klovinal Vaginal Tablet

Can a virgin use Klovinal Vaginal Tablet?

Yes, of course. Virgins are not immune to vaginal yeast infections or bacterial vaginosis since not all vaginal illnesses are sexually transmitted.

Virgins suffering from any of these conditions may safely use Klovinal. There's no need to be concerned; correctly injecting Klovinal will not cause your hymen to rupture. When using the inserter or applicator, use caution.

How long does Klovinal take to dissolve?

Within 10–15 minutes of insertion, a correctly placed Klovinal vaginal pessary dissolves.

Can I Take Klovinal Tablets During My Period?

If you've already begun therapy, yes. Do not disrupt the therapy process. Continue until you've completed the recommended course.

If your period has just begun and you have just been prescribed, you may begin if the infection is severe. If not, you should wait till your period is over. Using Klovinal during your period might be a pain.