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- Types of Neoplasm
- Causes of neoplasm
- Effects of Neoplasm on human
- Treatment of Neoplasm
- Breast Neoplasms
The term Neoplasm is a Greek word which means Noes-New, plasma-tissue
Types of Neoplasm
A benign tumor
- Slow growing
- Encapsulated
- Margin well defined
- Do not spread to other organs than that direct extension
- Benign tumors which arise from both epithelial and connective tissue are usually referred to with a name and a phrase called " Lomas"
Malignant Tumor
- Grow more rapidly
- Margins are I'll define
- Infiltrate to surrounding tissue
- Malignant tumor of epithelial origin is called " carcinoma" while that of connective tissue or mesodermal origin are called " sarcoma"
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Malignant Tumor may form metastasis
Metastasis - This means invasiveness to distant organs. This can be by:
- Direct spread
- Via lymphatic
- Via bloodstream
- Through body cavities
Causes of neoplasm
These are sometimes referred to as carcinogenic agents
- Smoking
- Alcohol
- Syphilis
- Nutritional Deficiency
- Sunlight
- Trauma or dental irritation
- Virus e.g epsten bar (E.B) virus
- Premalignant lesion e.g. leucoplakia
- Vitamin deficiency
- Oral sepsis.
Effects of Neoplasm on human
This depends on the site of a tumor
- Obstruction
- Pathological fracture
- Hemorrhage
- Infection
- Fever
- Cachexia (a) Anorexia (b) malabsorption
- Anemia.
Treatment of Neoplasm
- Chemotherapy
- Surgery.
- Radiotherapy
- A combination. For example; both chemotherapy and surgery
Breast Neoplasms
There are many types of breast Neoplasms, which can be divided into the following broad oversimplified categories as a starting point.
- intralobular (epithelial and stromal)
- interlobular
- breast lymphoma
- metastasis to breast
Intralobular and interlobular refer to the terminal duct lobular unit.
Although many of the epithelial lesions/changes listed below are neoplastic, they are best thought of as neoplasms at increased risk and along a continuum with normal breast at one end and invasive carcinoma at the other.
References
- 1. Muttarak M, Lerttumnongtum P, Chaiwun B et-al. Spectrum of papillary lesions of the breast: clinical, imaging, and pathologic correlation. AJR Am J Roentgenol. 2008;191 (3): 700-7. doi:10.2214/AJR.07.3483 - Pubmed citation
- 2. Kalisher L, Rickert RR, Sharo RJ. Solitary peripheral papilloma of the breast Neoplasm: a radiologic-pathologic correlation of a benign lesion that may mimic breast cancer on mammography. AJR Am J Roentgenol. 1998;171 (3): 605-9. AJR Am J Roentgenol (abstract) - Pubmed citation